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Hip-hop heals in Canadian MCs' guide to evolutionary medicine and the Darwinian roots of disease. Explore music. Pudding Is Delicious by Illbotz. Kattywampus Feanyx. Kattywampus Feanyx How could anyone not get cheered up after hearing that song? Favorite track: Give A Little Love.
Magnetic Dinosaurs | Sensory Oasis For Kids
Darryl Pierce. David Kinsel. Regis Murphy. Matt Robinson. Chadley Fox. Arthur Brazier. Robert Jennings. Michael Naughton. James "Sam" Magann. Christopher Sutton. Rusty Shackles. Tom B. Adam Argyle. Joshua Maher. Jacob Frelinger. Chad Walker. John-Wayne Witt. These results extend this work and are the first to show that this stress reaches down to the biological level, impacting the well accepted marker of aging and disease risk, telomere length," says Ridout.
Sen notes that after the discovery that telomeres protect the DNA in chromosomes from damage -- a discovery that earned the Nobel Prize -- research on them in humans has focused on taking snapshots of telomere length, mainly in older adults. This has yielded important discoveries about the links between shrunken telomeres and disease. Ridout analyzed data from dozens of telomere studies for a meta analysis published in that showed clear links between telomere length and the risk and severity of depression.
In the new study, Sen and his colleagues asked recently graduated medical students to contribute a sample of their DNA before they began their intern year, and then followed up to get another sample at the end of that year. The interns also took a lengthy questionnaire before their training began, and again at several points during and at the end of the intense year.
The results show that some new doctors went into residency with telomeres that were already shorter than their peers. This included those who said their family environment early in life was especially stressful -- which echoes previous findings about the impacts of such an upbringing on telomere length. Those who scored high on personality traits that together are classed as "neuroticism" -- being quick to react and slow to relax, and a tendency to respond with negativity -- also had shorter telomeres at the start of intern year.
But when the team looked at the results of the DNA tests taken after intern year ended, only one factor that they studied emerged with a clear link to telomere shrinkage: the number of hours the interns worked each week. On average, all the interns in the study said they worked an average of But the more the interns worked, and therefore the more days they put in that were at or above the national limit of 16 hours in effect at the time, the faster their telomeres shrank.
By contrast, the comparison group of 84 first-year U-M undergraduate students experienced no telomere shrinkage, despite also being in a stressful year-long situation of coping with life at an elite institution of higher education. Sen's Intern Health Study has begun collecting DNA samples from many more interns, and is now monitoring their mood, sleep and activity using smartphone apps and commercial activity trackers. He hopes to study the telomeres of future groups of interns to gather more data about how they change over the intern year and how those changes match up with their experiences during the year.
For instance, the frequent changes in shift time -- from day to night and back again -- during residency has already emerged in Sen's work as an important factor in mood and circadian disruption. Future studies will explore if this sort of shiftwork increases telomere attrition. He also hopes that researchers can evaluate whether any practices can protect telomeres from shrinkage or even spur repair and lengthening of these protective stretches of DNA. Like most people, I lack the willpower for a wholehearted plunge, but I've wondered what it would be like to let full-blown vanity sail me out over the steep canyons of unbridled rivalry.
Drawing back seems as ignoble as letting go, since it doesn't end the base emotions; it merely manages them. In Cope and Marsh, I saw a classic story of those who had not drawn back, and I wanted to explore it. This was partly as ignoble as my own recoil from the abyss; I wanted to enjoy vicariously the vanity balloon ascension while witnessing the historical punishment of the daredevils who had risked it.
But there may have been something of the nobler instinct that draws people to tragedy. I wanted to know what, if any, wisdom or transcendence might lie beyond the folly of unrestrained rivalry. The Herald evidently was on to something more than an esoteric argument, which raises a question of why the paper devoted so much space to the feud. Memoirs and histories largely have attributed the Herald's role to the only bylined author of the coverage, an associate of Cope's named William Hosea Ballou.
Having assumed that Ballou was on the Herald staff, they took for granted the newspaper's participation. Evidence, however, suggests that Ballou was not a Herald staffer, that he was not even a professional journalist; he was a barely competent free-lancer who wrote only part of the Herald's bone-war coverage and bungled that, faking interviews and infuriating named sources.
An eminent paleontologist, Alfred S. Romer, later said of Ballou that if scientists "merely passed the time of day with him, they were liable to be misquoted for a column or so. Like many monsters, this one preferred to operate in the background, and I found little uncircumstantial evidence of his involvement. But as I read what is known about him, I sensed that he offered the beginning of an explanation not only of the Herald's involvement in the feud, but of its historical resonance.
James Gordon Bennett, Jr. More than any journalist before William Randolph Hearst, who imitated him, Bennett not only reported history but made it, and the period from to bore his unmistakable stamp. History would have been quite different, for example, if Bennett hadn't sent Henry M.
Stanley to Africa. Yet Bennett's character was so repellent that it has obscured his historical role. Bennett by reflecting that the protagonist deserved a serious scholarly study but wasn't going to get one from him because he was too preposterous. Bennett's photos support O'Connor's Krafft-Ebing vision, showing a kind of debauched dragoon with a strangely narrow head punctuated by a fleshy nose and small, close-set, furiously staring eyes.
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In fact, Bennett was an alcoholic sociopath who committed a crowning sexual peccadillo so embarrassing that it still makes a reader squirm, over a century later. So it's no wonder historians have shied away from James Gordon Bennett, Jr. As it happens, he was a controlled alcoholic sociopath who knew what he wanted and pursued his desires with the sociopath's singleminded energy. He may have deliberately committed parlor urination to escape his engagement without incurring a costly breach-of-promise suit.
He also was a fabulously rich alcoholic sociopath who could enact his desires on a grand scale.
He had virtually absolute control over his newspapers. Bennett "regarded every word printed by his papers as emanating from himself," O'Connor wrote. The paper first captured public attention with a story featuring a rapt description of a murdered prostitute's nude corpse as surpassing "in every respect, the Venus de Medici. The Herald's Civil War coverage was unprecedented in its speed and thoroughness. After becoming publisher in , Bennett Jr.
Sometimes he simply lied, as when, in November , the Herald reported that escaped zoo animals had mauled people in Central Park. More often, Bennett chose a real sensation and injected one of his zombies into it as actor-reporter. The most famous zombie, of course, was Stanley, a nonalcoholic sociopath who might have ended on the gallows his crimes included extortion, assault, and desertion from both the Confederate Army and Union Navy if the Herald had not hired him in the late s.
His epic search for the missionary-explorer Dr. David Livingstone was more a product of Bennett's imagination than of Stanley's, as the publisher was quick to insist.
Shoestrings-No Time for Dinosaurs
Stanley had cared little about Livingstone until Bennett summoned him to his Paris hotel and declared, "I think he is alive and that he can be found, and I am going to send you to find him. The publisher's obsession with penetrating the unknown not only reflected the nineteenth century's exploration vogue, but magnified it. Perhaps one reason he hasn't been called great is that, unlike Stanley, he made little pretense of acting for the benefit of civilization. He said he supported exploration to sell newspapers, but he was disingenuous even in that cynical attitude.
At heart, Bennett seems to have been not merely indifferent, but hostile, to civilization's benefit.
His zoo hoax suggests a fascination not with taming savagery but with savagery's potential for dissolving civilized constraints, which he found irksome. Livingstone's saintly aura probably interested him less than the allegations of brutality and consorting with native women that led Joseph Conrad to model, in part, his Heart of Darkness anti-hero, Kurtz, on the missionary. Bennett might have found some satisfaction by exploring Africa himself, Kurtz-fashion. He didn't lack physical courage; he raced his yacht across the Atlantic more than once. But he was unwilling to forgo luxuries, and knew he lacked the stomach for the extreme hardships of nineteenth-century expeditions.
This didn't stop him from bitterly envying the fame of those who did explore, and from feeling that he deserved it. In , he sent a reporter to the Tyrolean resort where Stanley was vacationing in an attempt to confirm rumors that the explorer beat his wife. Not even innocent bystanders escaped his spite. In swanky restaurants, he would amuse himself by yanking off other diners' tablecloths while well-bribed waiters stood by.